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Benign prostatic hyperplasia (BPH)

What is BPH?
BPH Benign prostatic hyperplasia is a progressive disease defined histologically and characterized by stromal and epithelial cell hyperplasia beginning in the periurethral zone of the prostate.1,2 The chief complaint of the patient with BPH is usually bothersome LUTS typified by urinary frequency, urgency, nocturia, decreased and intermittent force of stream and the sensation of incomplete bladder emptying.

BPH is often associated with enlargement of the prostate (BPE). However the relationship between BPH, LUTS (Lower Urinary Tract Symptoms) and BPE is complex and not all patients with BPH will have LUTS or BPE and also (BPE) may exist in the absence of LUTS.

Is it common?
BPH is one of the most common conditions affecting older men and can cause major disruption in everyday life (Marks et al 2006).

The presence of Lower Urinary Tract Symptoms (LUTS) although not specific or exclusive of BPH are characteristic of this disease.

Management of BPH
The management of BPH should focus on the long-term improvement of patients' symptoms, improving quality of life, and relieving or preventing the development of serious secondary conditions. Options range from no active treatment (termed 'watchful waiting'), through drug therapy, to surgical intervention.

Useful links:

  • Prostate UK:
    We fund medical research, the training of healthcare professionals and provide information on all prostate diseases.  We actively campaign to raise public awareness.

  • Netdoctor: 
    We want to break down the "medical language barrier" between the doctor and the patient. Critical medical information must be presented in a clear and understandable language so that the patient fully understands his or her choices and decisions. Ultimately, it is the patient who must make the critical health choices.

Source: EPG guide- www.epgonline.org/benign-prostatic-hyperplasia.cfm

References
1. Lee, C., Cockett, A., Cussenot, K., Griffiths, K., Isaacs, W., and Schalken. “Regulation of Prostate Growth”. In: Proceedings of the Fifth International Consultation on BenignProstatic Hyperplasia. Edited by C. Chatelain, L. Denis, K.T. Foo, S. Khoury, and J. McConnell. United Kingdom: Health Publications Ltd., chapt. 3, 79-106, 2001.
2. McNeal, J. E. Origin and evolution of benign prostatic enlargement. Invest Urol, 15: 340, 1978.

Last Updated 25-05-2010