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International diabetes study challenges US trial findings
14 Feb 2008
An international study into intensive treatment in type 2 diabetes has contradicted the results of an earlier trial in the US.
Reuters reports that the largest-ever study of measures to control blood sugar levels in type 2 diabetics with intensive treatment has found that the process does not lead to a higher risk of death.
The latest set of results opposes findings by a US trial which showed a slight increase in deaths in diabetics whose blood sugar had been reduced to near-normal levels, Reuters reports.
Previously, the Accord study findings aimed to challenge conventional thinking about diabetes control, that lowering blood glucose to the normal range can protect patients against blindness and other diabetes-linked illnesses.
However, a team from the University of Sydney, dubbed Advance, checked to see whether diabetics undergoing similar intensive drug therapy also had a higher risk of death.
Their results, based on more than twice as much data (11,140 high-risk patients) and similar levels of glucose, found little evidence to back up the Accord findings.
"The interim results from Advance provide no confirmation of the adverse mortality trend reported from the Accord study," Rory Collins of the University of Oxford, said in a statement.
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