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Osteoporosis bisphosphonates link in doubt

20 Feb 2008

Bisphosphonates used to treat osteoporosis have been found to have little effect on sufferers of osteonecrosis of the jaw (ONJ), new research suggests.

Bisphosphonates are currently used to help prevent the sometimes debilitating bone fractures in people living with osteoporosis.

However a US study of 7,000 patients found that the use of bisphosphonates to treat osteopororsis has little or no effect on the incidence of osteonecrosis.

The first reported cases of ONJ first came to light as recently as 2003, in patients who were using bisphosphonates.

ONJ, characterised by bone necrosis and prolonged exposure of the jaw bone to the oral cavity, often occurs in older people who have experienced an oral surgical procedure.

The findings were presented at the American Academy for the Advancement of Science news conference by John Grbic from Columbia University's College of Dental Medicine.

According to the International Osteoporosis Foundation, osteoporosis causes one fracture every 30 seconds Europe-wide.

Click here to find out more about osteoporosisADNFCR-1528-ID-18473541-ADNFCR

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