21 Feb 2008
Advice to consume glucosamine to ease arthritis symptoms may have no actual benefits on pain or progression of arthritis of the hip, a new study claims.
A team from the Erasmus Medical Centre in Rotterdam randomly gave 222 hip arthritis sufferers 1,500 milligrams of the nutritional supplement daily or a placebo over the course of two years, the Annals of Internal Medicine reports.
Researchers found that glucosamine had no significant effect on pain, physical function, stiffness, use of pain medication or progression of the disease.
They took precautions to ensure that each participant was given the correct dose of glucosamine, while physicians, patients and researchers were blinded to group assignment.
The report's authors wrote that definitive evidence of glucosamine's efficacy is currently lacking.
This has been linked to non-standardised glucosamine preparations, inadequate "blinding" in studies, and differences in outcome measures.
Glucosamine, an amino acid, is a natural substance occurring naturally in healthy joint cartilage.
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