29 Mar 2008
Taking anti-depressants can lead to an increased risk of diabetes, according to new research published in the Diabetes Research and Clinical Practice journal.
Lauren Brown from the School of Public Health at the University of Alberta found that patients who take both tricyclic anti-depressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) are twice as likely to develop type 2 diabetes.
The researcher also found a 30 per cent higher risk of type 2 diabetes in patients with a history of depression.
Of the 2,400 participants, the study identified four different groups of people: those using older anti-depressants; those taking newer drugs; those using a combination of drugs; and those who were switching between treatments.
Ms Brown found that patients who took both SSRIs and TCAs had a higher incidence of diabetes, suggesting that this highlights the need for diabetes screening in depression sufferers.
However, she added that this combination of drugs is a rare occurrence, with just ten per cent of the research sample taking SSRIs alongside TCAs.
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