19 May 2008
Almost 40 per cent of gastroesophageal reflux disease (GERD) patients continue to experience symptoms such as acid regurgitation and heartburn, despite daily use of proton pump inhibitors (PPIs), research reveals.
A new survey of 1,064 people conducted by the American Gastroenterological Association (AGA) Institute found that these returning "breakthrough" symptoms result in more than half (56 per cent) of GERD patients turning to over-the-counter remedies.
According to the AGA's findings, over 70 per cent of GERD sufferers use over-the counter medications in addition to prescribed PPIs to manage and control symptoms.
The findings indicated that 65 per cent of GERD sufferers experienced breakthrough at night and 28 per cent report sleep disruption as a result.
Dr John Inadomi, associate professor of medicine at the University of California, San Francisco, commented: "Breakthrough symptoms can be bothersome and frustrating to GERD sufferers, but they aren't talking about it with their physician as often as they should.
"By discussing the frequency, severity and timing of breakthrough symptoms, physicians and patients can determine if changes need to be made to their GERD treatment."
Participants of the study were 40 per cent male, 60 per cent female. All patients had been taking a PPI to control their GERD symptoms for a minimum period of three months.
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